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Having said that, in the skincare world there is increasing anecdotal evidence that applying MSM can leave skin feeling softer and smoother. For example, MSM may be effective in reducing oxidative stress and inflammation that can weaken immunity. Since it’s effective in reducing levels of inflammatory compounds like IL-6 and TNF-ɑ, MSM may reduce stress on your immune system. MSM seems to be well-tolerated, since it’s completely natural and already found in the human body. There haven’t been many serious side effects of MSM reported to date, however, there also haven’t been many large, well-controlled human studies looking at its long-term effects. This helps keep us hydrated and lowers inflammation, which is the root of most diseases. Research shows that MSM also stabilizes cell membranes, improves the body’s antioxidant abilities, slows or stops leakage from injured cells, and scavenges hydroxyl free radicals.
Keep in mind that many MSM supplements contain synthetic byproducts and fillers. You want to look for an organic brand that sells “100% naturally derived MSM.” Benefits 1. Treats Osteoarthritis and Joint Pain Most people can tolerate doses of MSM up to 4000mg (4g), but consult a health professional before starting to take MSM. 24 She says that it helps her to recover so she can be at her best when playing tennis. There is no doubt that this cream works. Debbi EM, Agar G, Fichman G, et al. Efficacy of methylsulfonylmethane supplementation on osteoarthritis of the knee: a randomized controlled study. BMC Complement Altern Med. 2011 Jun 27;11:50. View abstract. A study in 100 people over the age of 50 found that treatment with a supplement containing 1,200 mg of MSM for 12 weeks decreased pain, stiffness and swelling in the joints, compared to a placebo ( 2).MSM is also believed to help calm inflammatory conditions such as allergic rhinitis; hay fever is a type of allergic rhinitis. 2
That being said, it is capable of causing mild side effects for some people, including indigestion, upset stomach, diarrhea, and skin and eye irritation. It’s also not suitable for people taking blood-thinner medications, due to potential side effects affecting the heart and cardiovascular system that may occur. Medical News Today has strict sourcing guidelines and draws only from peer-reviewed studies, academic research institutions, and medical journals and associations. We avoid using tertiary references. We link primary sources — including studies, scientific references, and statistics — within each article and also list them in the resources section at the bottom of our articles. You can learn more about how we ensure our content is accurate and current by reading our editorial policy. This may explain why it’s a popular arthritis remedy; a 2004 study of 118 people with osteoarthritis found those taking MSM, glucosamine, or a combination of both, showed a significant improvement in pain and joint swelling compared with those taking a placebo. 6
What does MSM stand for?
A study of 16 untrained healthy males, which suggests that taking an MSM supplement helps reduce biomarkers of oxidative stress after exercise. It also increased the total antioxidant capacity of their blood. Therefore the dosage you’ll want to take depends on what you’re using MSM for and your current state of health.
According to the Arthritis Foundation, based on the most reputable studies conducted so far on this supplement — such as a 2006 pilot study that analyzed the effects of 6,000 milligrams of MSM taken daily by patients with osteoarthritis — it effectively helps improve symptoms of pain and physical function without any major side effects. Limited small studies also show that MSM may help with exercise recovery. But researchers have more work to do to confirm this. Sulfur needs to be present for our cells to release many byproducts and excess fluids that can accumulate and cause swelling/tenderness. Barmaki S, Bohlooli S, Khoshkhahesh F, et al. Effect of methylsulfonylmethane supplementation on exercise - Induced muscle damage and total antioxidant capacity. J Sports Med Phys Fitness. 2012 Apr;52:170-4. View abstract. MSM benefits include: treating osteoarthritis and joint pain; improving digestive problems like leaky gut syndrome; repairing skin problems like rosacea and wounds; lowering muscle pain and spasms; restoring hair growth and helping the body adapt to stress and allergies.
Can you use MSM topical? What is MSM cream good for?
The Influence of Methylsulfonylmethane on Inflammation-Associated Cytokine Release before and following Strenuous Exercise Joint pain. Research shows that taking a specific combination product (Instaflex Joint Support, Direct Digital, Charlotte, NC) containing MSM daily for 8 weeks reduces joint pain. But this product does not seem to improve stiffness or function. A study in 18 men showed that taking 50 mg of MSM powder per kg of body weight for 10 days significantly reduced exercise-induced muscle damage and increased antioxidant activity following an 8.7 mile (14 km) run ( 9). Pagonis, T. A., et al. (2014). The effect of methylsulfonylmethane on osteoarthriticlarge joints and mobility.
Berardesca E, Cameli N, Cavallotti C, et al. Combined effects of silymarin and methylsulfonylmethane in the management of rosacea: clinical and instrumental evaluation. J Cosmet Dermatol. 2008 Mar;7:8-14. View abstract. Berardesca, E., et al. (2008). Combined effects of silymarin and methylsulfonylmethane in the management of rosacea: clinical and instrumental evaluation [Abstract]. MSM can help rebuild the lining of the digestive tract and lower inflammatory responses in response to allergic reactions to certain foods.One study found that combining MSM with glucosamine and chondroitin was more effective at decreasing pain and stiffness in people with knee osteoarthritis than glucosamine and chondroitin alone ( 13). This MSM lotion by Sunfood is another great product to use as a daily moisturizer. By combining organic vitamins and botanicals, this product is not only effective, but smells incredible.
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