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The hibiscus flower is much more than just a pretty bloom; it's a symbol that carries deep cultural meanings across the globe. In many societies, the hibiscus represents beauty, love, and fertility, often featured in celebrations like weddings. In Hawaii, the hibiscus encapsulates the "Aloha spirit," signifying warmth, hospitality, and friendliness. Additionally, this radiant flower holds a place of honour as the national flower of Malaysia, where it is known as "Bunga Raya" and stands as a symbol of courage. Several human trials have found that hibiscus beverages and supplements can decrease blood pressure ( 11, 12).
Bacteria are single-celled microorganisms that can cause a variety of infections, such as bronchitis, pneumonia, and urinary tract infections. Both MDA-MB-231 and MCF-7 cells were additionally treated with tamoxifen, taxol, and cisplatin to compare the induction of apoptosis between standard chemotherapeutic treatments and HE. In both cell lines, tamoxifen and cisplatin treatments did not significantly induce apoptosis and taxol significantly induced apoptosis only in MDA-MB-231 cells (Fig. 1a). HE treatment at 4 mg/mL caused significant induction of apoptosis at a comparable or greater level to all chemotherapeutics tested.
The hibiscus flower is common in tropical areas and has been utilised in ancient medicine for many years. Women also wear hibiscus flowers as hair accessories because of their vibrant colours. However, the tropical flower is more than just a gorgeous garden and hair adornment. The hibiscus plant’s leaves and flowers make hibiscus essential oil, which is said to be equally effective as coconut oil. Furthermore, hibiscus oil contains a high concentration of antioxidants, vitamins A and C, and Alpha-Hydroxy Acids and Amino Acids. This makes it the ideal deep conditioning treatment for your skin and hair. Hibiscus oil improves hair growth, gloss, and prevents premature greying and dandruff when applied to hair. What are the surprising hibiscus hair oil benefits? 1. Helps in hair growth To withdraw the extract, strain the oil. Make sure there’s no flower debris. Here’s a 4-step guide: It significantly reduces hair loss, moisturises the scalp, and strengthens hair follicles. It is especially beneficial for hair fall brought on by chemical use, contaminated water, pollution exposure, and inadequate nutrition for the scalp. The oil is rich in essential nutrients and amino acids due to the combination of herbs, curry leaves, hibiscus, and neem leaves. These nutrients help to strengthen hair follicles, minimise hair loss, and promote hair growth. Since growing up surrounded by bright red hibiscus flowers, anything hibiscus’ will always be a rich, vibrant red color. We have investigated aqueous hibiscus flower extract anticancer efficacy, selectivity, and interactions with chemotherapeutics taxol, cisplatin, and tamoxifen in estrogen-receptor positive breast cancer cells, triple-negative human breast cancer cells, and normal non-cancerous cells. Apoptotic morphology and biochemical marker expression were assessed to determine the extent anticancer efficacy of hibiscus. Mitochondrial membrane potential reduction and reactive oxygen species generation were quantified using fluorogenic dyes to determine the mechanism of hibiscus extract action. Results
To further investigate the benefit of using a combination treatment of HE with chemotherapeutics, taxol and hibiscus combination treatments were compared to individual treatments of taxol on NHF cells. On their own, chemotherapeutics treatments showed toxicity (Fig. 4b). They are non-selective compared to hibiscus. Most surprisingly, HE combination treatments did not lead to increased apoptosis induction when compared to individual treatments, but instead lowered the amount of apoptosis induction observed (Fig. 4b). These results indicate that HE shows selectivity to breast cancer cells and potentially protects normal human healthy cells from being affected by chemotherapeutic treatments. Hibiscus extract is able to induce apoptosis in breast cancer cells by increasing oxidative stress and targeting the mitochondria Another test-tube study showed that the extract fought eight strains of bacteria and was as effective as some medications used to treat bacterial infections ( 27). Philion C, Ma D, Ruvinov I, et al. Cymbopogon citratus and Camellia sinensis extracts selectively induce apoptosis in cancer cells and reduce growth of lymphoma xenografts in vivo. Oncotarget. 2017;8(67):110756–73. Published 2017 Nov 18. https://doi.org/10.18632/oncotarget.22502. In addition to lowering blood pressure, some studies have found that hibiscus tea may help improve blood fat levels, which can be another risk factor for heart disease ( 9).
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Hibiscus seed oil is a special oil too. It is a delicate and lovely carrier oil, and it is a powerful lipid on its own as a facial oil. Fatty Acid Profile Shah R, Rosso K, Nathanson SD. Pathogenesis, prevention, diagnosis and treatment of breast cancer. World J Clin Oncol. 2014;5(3):283–98. Hibiscus extract was able to selectively induce apoptosis in both triple-negative and estrogen-receptor positive breast cancer cells in a dosage-dependent manner. Most importantly, addition of hibiscus extract was found to enhance the induction of apoptosis of chemotherapy treatments (taxol and cisplatin) in triple-negative breast cancer cells when compared to treatment alone. Moreover, hibiscus extract addition to chemotherapy treatment was able to increase oxidative stress and decrease mitochondrial membrane potential compared to individual treatments. Conclusion Herranz-López M, Olivares-Vicente M, Encinar JA, et al. Multi-targeted molecular effects of Hibiscus sabdariffa polyphenols: an opportunity for a global approach to obesity. Nutrients. 2017;9(8):907. Published 2017 Aug 20. https://doi.org/10.3390/nu9080907. StarJo – Hibiscus hair oil is very moisturizing. It's great for my hair, which has been damaged by various chemical processes like perms and coloring.
Some research indicates that prolonged use of high doses of hibiscus extract may cause liver injury. Hibiscus could also interact with certain medications ( 3). If this doesn't make you want to try out hibiscus oil for hair growth , we do not know what will. Grab a pen and a paper to note down the recipe to make hibiscus oil for hair and why you need to have it in your hair care routine. Benefits of hibiscus oil for hair Hibiscus seeds are harvested and dried to reduce their moisture content. This is crucial, as excess moisture can affect the oil's quality and longevity. Additionally, the emollient properties of hibiscus oil make it an excellent moisturizer for dry and damaged hair. Its rich, moisturizing properties strengthen hair and restore its natural shine. Hibiscus oil can also help to balance the pH of your scalp, preventing issues like dandruff and scalp irritation. These reasons are why we love hibiscus for hair and have included it in our list of best hair oils. Hibiscus Oil for Cleansing
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The mechanism of apoptosis induction in breast cancer is a topic of great interest to determine the underlying cause of cell death. Previously, we have shown that ethanolic extracts of lemongrass and aqueous extracts of dandelion root were able to induce oxidative stress and decrease mitochondrial membrane potential, leading to apoptosis induction in cancer cells [ 18, 19]. While the exact mechanism is not yet clear, it has been hypothesized that high ROS levels can activate cellular stress mechanisms and may sensitize cancer cells to further ROS production leading to apoptosis [ 9]. Indeed, our results indicate that HE treatment led to increased ROS generation in both triple-negative and ER+ breast cancer cells (Fig. 5). Moreover, taxol and cisplatin treatments in combination with HE showed increased ROS generation when compared to individual treatments. This helps explain the increase in apoptosis induction of combination treatments compared to individual treatments as discussed above (Figs. 3, 4). It should be noted that triple-negative breast cancer cells were more vulnerable to oxidative stress than ER-positive breast cancer cells. These are two different cells with varied susceptibilities, and the lowered ROS generation of ER-positive breast cancer treatment indicates either an alternate mechanism of apoptosis induction or a need for increased dosage. Further, we have demonstrated that HE combination treatment is able to enhance the mitochondrial membrane potential reduction in breast cancer cells (Fig. 6). The breast cancer cell line MCF-7 (ATCC® HTB-22™) were cultured in Dulbecco’s Modified Eagle’s Medium (DMEM) (ATCC® 30–2002™) supplemented with 10% ( v/v) fetal bovine serum (FBS, Thermo Scientific, Waltham, MA, USA, Cat No. 12484–020) and 0.4% ( v/v) gentamicin (Gibco BRL, VWR, Mississauga, ON, CA Cat No. 15710–064). Hibiscus oil contains Alpha Hydroxy Acids also known as AHA, which helps in exfoliation of the skin. It contains the natural acids that help to nourish and exfoliate the skin. Also, applying hibiscus oil on any part of the body sheds the dead skin cells and works as a scrub to that area. If you want to make the scrub more effective just add hibiscus oil in your regular homemade scrub.
Anders C, Carey LA. Understanding and treating triple-negative breast cancer. Oncology (Williston Park). 2008;22(11):1233–9 discussion 1239–40, 1243. Hibiscus Oil is made from the Hibiscus plant's flowers. Hibiscus flowers have been used for their medicinal properties since ancient times. It contains vitamin A, vitamin C, amino acids, alpha-hydroxy acids, and powerful antioxidants that prove beneficial for both skin and hair. When my skin is dry, it gets very itchy. Hibiscus oil prevents the itchiness and burning associated with winter dryness.
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Trottier G, Boström PJ, Lawrentschuk N, Fleshner NE. Nutraceuticals and prostate cancer prevention: a current review. Nat Rev Urol. 2010;7(1):21–30. https://doi.org/10.1038/nrurol.2009.234. Hibiscus oil has a balanced fatty acid profile that leans towards being more moisturizing and better for drier skin types due to higher levels of oleic acid. The Oleic acid content usually ranges 35-40% and is well-balanced by 25-35% linoleic acid. Having these two critical fatty acids balanced in that proportion results in an oil that's anti-inflammatory as well as moisturizing while being very unlikely to clog pores. Will Hibiscus Oil Clog Pores
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