Galpharm Treathay Hayfever Relief Fexofenadine, 30 Count (Pack of 1)

Product Information

For adults and children aged 12 years and over: Take one tablet (120 mg) daily. Take the tablet with water before a meal.

Fexofenadine does not undergo hepatic biotransformation and therefore will not interact with other medicinal products through hepatic mechanisms. Coadministration of fexofenadine hydrochloride with erythromycin or ketoconazole has been found to result in a 2–3 times increase in the level of fexofenadine in plasma. The changes were not accompanied by any effects on the QT interval and were not associated with any increase in adverse reactions compared to the medicinal products given singly.Each film-coated tablet contains 120 mg of fexofenadine hydrochloride, which is equivalent to 112 mg of fexofenadine. The proposed mechanism is inhibition of drug efflux via intestinal organic anion transporting polypeptides (e.g., P-glycoprotein), of which fexofenadine is a substrate. Limited animal studies do not indicate direct or indirect harmful effects with respect to effects on pregnancy, embryonal/foetal development, parturition or postnatal development (see section 5.3) . TREATHAY 120 mg tablets should not be used during pregnancy unless on the advice of a doctor.

Human histamine wheal and flare studies following single and twice daily doses of fexofenadine hydrochloride demonstrate that the medicinal products exhibits an antihistaminic effect beginning within one hour, achieving maximum at 6 hours and lasting 24 hours. There is no evidence of tolerance to these effects after 28 days of dosing. A positive dose-response relationship between doses of 10mg to 130mg taken orally was found to exist. In this model of antihistaminic activity, it was found that doses of at least 130mg were required to achieve a consistent effect that was maintained over a 24 hour period. Maximum inhibition in skin wheal and flare areas was greater than 80%. Clinical studies conducted in seasonal allergic rhinitis have shown that a dose of 120mg is sufficient for 24 hour efficacy. Dizziness, drowsiness, fatigue and dry mouth have been reported with overdose of fexofenadine hydrochloride. Single doses up to 800 mg, and doses up to 690 mg twice daily for 1 month, or 240 mg once daily for 1 year have been administered to healthy subjects without the development of clinically significant adverse reactions as compared with placebo. The maximum tolerated dose of fexofenadine hydrochloride has not been established.

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The recommended dose of fexofenadine hydrochloride for adults is 120 mg once daily taken before a meal. Anti Malaria Malaria is a serious tropical disease spread by mosquitoes. If it isn’t diagnosed and treated promptly, it can be fatal. A single mosquito bite is all it takes for someone to become infected. Symptoms of malaria It’s important to be aware of the symptoms of malaria if you’re travelling to areas where there’s a high risk of the disease. Symptoms include: 1. A high temperature of 38C or above 2. Feeling hot and shivery 3. Headaches 4. Vomiting 5. Muscle pains 6. Diarrhoea Symptoms usually appear between 7 and 18 days after becoming infected, but in some cases the symptoms may not appear for up to a year, or occasionally even longer. When to seek medical attention Seek medical help immediately if you develop symptoms of malaria during or after a visit to an area where the disease is found. You should still seek medical help even if it’s several weeks, months or a year after you return from travelling. If there’s a possibility you have malaria, a blood test will be carried out to confirm whether or not you’re infected. You should receive the results of your blood test on the same day. If you have malaria, treatment will… Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicine. Indigestion remedies containing aluminium and magnesium may affect the action of TREATHAY by lowering the amount of medicinal product absorbed.

Each film-coated tablet contains 120 mg of fexofenadine hydrochloride, which is equivalent to 112 mg of fexofenadine. any medicine that makes you drowsy, gives you a dry mouth, or makes it difficult for you to pee – taking fexofenadine might make these side effects worse If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.

Studies in special risk groups (elderly, renally or hepatically impaired patients) indicate that it is not necessary to adjust the dose of fexofenadine hydrochloride in these patients. You may only need to take fexofenadine on a day you have symptoms, such as when you've been exposed to something you're allergic to, like animal hair. feeling dizzy – lie down until you do not feel dizzy anymore, then get up slowly. Move slowly and carefully. Avoid coffee, cigarettes, alcohol and recreational drugs. If the dizzy feeling does not get better within a couple of days, speak to your pharmacist or doctor.

No significant differences in QT c, intervals were observed in seasonal allergic rhinitis patients given fexofenadine hydrochloride up to 240 mg twice daily for 2 weeks when compared to placebo. Also, no significant change in QT c intervals was observed in healthy subjects given fexofenadine hydrochloride up to 60 mg twice daily for 6 months. 400 mg twice daily for 6.5 days and 240 mg once daily for 1 year, when compared to placebo. Fexofenadine at concentrations 32 times greater than the therapeutic concentration in man had no effect on the delayed rectifier K + channel cloned from human heart. If you're breastfeeding or planning to breastfeed, talk to your doctor or pharmacist, as other antihistamines called loratadine and cetirizine might be better while you're breastfeeding. The active ingredient in your tablets is fexofenadine hydrochloride, which belongs to a group of medicines called antihistamines. It can be used in adults and adolescents of 12 years and older to If symptoms persist or worsen, stop use and consult your doctor or pharmacist. Do not take more than one tablet in 24 hours.Fexofenadine hydrochloride was found to be non-mutagenic in various in vitro and in vivo mutagenicity tests. Limited animal studies do not indicate direct or indirect harmful effects with respect to effects on pregnancy, embryonal/foetal development, parturition or postnatal development (see section 5.3). TREATHAY 120 mg tablets should not be used during pregnancy unless on the advice of a doctor. In adults, the following undesirable effects have been reported in postmarketing surveillance. The frequency with which they occur is not known (can not be estimated from available data) If you forget to give a dose to a child who is taking fexofenadine twice a day, you can give the dose if it's within 4 hours of when they should have had it.